Chemotherapy regimen in ENT field is Chemotherapy is a cancer treatment by administering certain drugs (cytostatics/anti-cancer drugs). cancer) which aims to to inhibit growth cell cancer or kill cancer cells (1). These drugs are cytotoxic and have different mechanisms in causing cell death. (1). This chemotherapy refers to agents cytotoxic which own mechanism of action which can cause cell death, inhibiting growth cells, inhibiting microtubule function, function protein or DNA synthesis (2).